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The medial segment of the A1 was communicating with the left ACA via the Anterior communicating artery, while the lateral segment was directly joining the A2 segment of the same side. The computer tomography angiography showed a fenestration of the right A1 segment of the anterior cerebral artery (ACA). A 42-year-old hypertensive patient presented unconscious following a ruptured saccular aneurysm. We present a rare fenestration of the A1 segment of the anterior cerebral artery presenting with a ruptured saccular aneurysm. Their prevalence is not exactly known, as most of them are incidentally diagnosed on angiography or postmortem dissections. The aim of this study is to introduce the meanings of functional anatomy in the clinical application of vascular diseases and anomalous of the central nervous system.Ĭerebral vascular anatomical variations are not uncommon in the human population. This perception may facilitate better understanding of the vascular pathologies and lead to the appropriate decision making not only in the diagnostic work, but also in the interventional procedures. In addition, learning more about the hemodynamic consequence may help to realize the underlying physiopathology of cerebral arterial remodeling and stroke in patients with these vascular variants. Such an embryological parallelism like the comparative anatomy provides the new insights into the nature of our vascular system. Thus, it is possible to deduce the reasons of vascular variants in terms of phylogeny. The most developmental process is common among the species of the vertebrates from the fish to the mammalian in the early phase of embryo. fenestration of the basilar artery, persistent primitive trigeminal artery, and aberrant subclavian artery) can be explained according to the embryological development of the cardiovascular system. The mechanism of anatomical variations (e.g.

Functional vascular anatomy is the study of anatomy in its relation to the function that figures out the normal and pathological vascularization of the brain and spinal cord.